Perfluorosorb® S is a fluorocarbon based polymeric adsorbent for the purification of plasmid DNA using a reverse-phase chromatographic approach. It’s highly porous structure, broad pH resistance and high binding capacity make it ideal for purification of supercoiled pDNA. Uniquely, the exceptional robustness of this adsorbent allows regeneration and depyrogenation with concentrated sodium hydroxide which enables its use for repetitive purification cycles. Perfluorosorb® S is used commercially by producers of high-grade DNA intended for use in therapeutic applications. It is available in slurry and pre-packed column kit formats and may be used for the following applications:

• Primary capture of cc DNA, post-cell lysis and clarification.

• As a polishing agent after ion exchange chromatography to remove endotoxin, genomic DNA, oc and other DNA isoforms, m RNA and protein.

Available in the following standard formats:
Suspension for column packing available in 25ml/100ml/500ml/1000ml;
Pre-packed columns (5×1ml) (for attachment to chromatography workstations);
PuraPlate™ (96 column plate for rapid antibody screening and purification method development).

We also offer a range of larger pack sizes for supply of bulk resins into cGMP development and manufacturing scale processes. For more information on this or any other supply related matters please do not hesitate to contact us on sales@prometicbiosciences.com